Organic Chemistry
Consulting Services

// Small Molecule Design & Synthesis Expertise

Professional organic chemistry consulting with 10+ years of experience in medicinal chemistry, custom synthesis, and pharmaceutical route optimization. From concept to commercialization.

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Expert Services

// Comprehensive Organic Chemistry Solutions

Custom Synthesis

Design and execute complex multi-step syntheses for pharmaceutical intermediates, natural products, and specialty chemicals. Expert in asymmetric synthesis and stereochemistry control.

Route Optimization

Streamline existing synthetic pathways to reduce steps, improve yields, and minimize costs. Process chemistry expertise for scale-up and manufacturing optimization.

Molecular Design

Structure-activity relationship analysis and molecular design for drug discovery. Computational chemistry support and retrosynthetic analysis for complex targets.

Literature Research

Comprehensive patent and literature searches. Competitive intelligence and freedom-to-operate analysis. Technical due diligence for pharmaceutical investments.

Process Development

Scale-up chemistry from laboratory to manufacturing. Process safety evaluation, impurity profiling, and regulatory submission support for pharmaceutical processes.

Training & Education

Technical training for R&D teams. Workshops on modern synthetic methods, reaction mechanisms, and problem-solving strategies in organic chemistry.

About Dr. Chen Wei

// Organic Chemistry PhD with Industrial Experience

Dr. Chen Wei
PhD in Organic Chemistry - Peking University (2012)
Senior Scientist - Novartis (2012-2018)
Lead Chemist - BeiGene (2018-2022)
20+ Publications in J. Am. Chem. Soc., Angew. Chem.
15+ Patents in Pharmaceutical Chemistry
Consultant for 50+ Biotech Companies
English, Chinese, German Fluent

Selected Projects

// Case Studies & Success Stories

Molecular Structure
Coming Soon

API Synthesis Optimization

Redesigned a 12-step synthesis route for a cardiovascular drug API, reducing to 6 steps with 45% overall yield improvement and 60% cost reduction. Key improvements included telescoped reactions and elimination of chromatographic purifications.

Process Chemistry Scale-up Cost Reduction
Natural Product
Structure

Natural Product Total Synthesis

First asymmetric total synthesis of a marine alkaloid with potent anti-cancer activity. 15-step route featuring innovative cascade cyclization reaction and excellent stereochemical control throughout the sequence.

Total Synthesis Stereochemistry Method Development
Compound Library
Preview

Pharmaceutical Intermediate Library

Designed and synthesized a focused library of 200+ heterocyclic compounds for a kinase inhibitor program, leading to 3 clinical candidates. Structure-activity relationships guided optimization strategy.

Med Chem SAR Drug Discovery
Green Chemistry
Route

Green Chemistry Implementation

Developed environmentally friendly synthesis route replacing toxic reagents and reducing waste by 80% for a diabetes treatment manufacturing process. Achieved same efficiency with safer reagents.

Green Chemistry Sustainability Manufacturing
Chiral Auxiliary
Design

Chiral Auxiliary Development

Designed novel chiral auxiliary for enantioselective synthesis of β-amino acids, achieving >95% ee with broad substrate scope and easy recovery. Patent application filed for this innovative methodology.

Asymmetric Synthesis Methodology Chirality
Alternative
Synthesis Route

Freedom-to-Operate Route Design

Developed alternative synthetic routes for blockbuster drug to avoid patent restrictions while maintaining cost-effectiveness for generic manufacturing. Successfully passed regulatory review.

Patent Analysis Generic Drugs IP Strategy

Client Feedback

// What Collaborators Say

Dr. Chen redesigned our route in six weeks and cut our COGS by nearly a third without touching the impurity profile. Communication was direct and the documentation was audit-ready from day one.

VP of Chemistry — Clinical-Stage Biotech, United States

We brought him in for a freedom-to-operate review before Series B diligence. The analysis was thorough enough that our investors' outside counsel had nothing to add.

Co-Founder & CSO — Small Molecule Startup, Europe

Our internal team was stuck on a stereochemistry problem for months. He proposed a cascade cyclization approach that worked on the first scaled attempt.

Director of Process Chemistry — CDMO, Asia-Pacific

Collaboration Process

// How We Work

01

Free Consultation

30-minute call to discuss your target molecule, timeline, and constraints.

02

NDA Signature

Mutual confidentiality agreement signed before any structures or data are shared.

03

Proposal & Quote

Detailed technical proposal with scope, milestones, and transparent pricing.

04

Project Execution

Hands-on synthesis or analysis work, with progress updates at each checkpoint.

05

Delivery

Final compounds and documentation handed over, with follow-up support as needed.

Let's Collaborate

// Ready to Start Your Next Project?

Email

[oriwoodwild@gmail.com]